Toxicological evaluation of endophyte-infected perennial ryegrass straw to Japanese Black steers

Authors

  • S. Miyazaki
  • T. Ikeda
  • M. Hanazumi
  • Y. Fukumoto
  • T. Yamata
  • O. Mikami
  • N. Yamanaka
  • H. Murata
  • N. Shimada
  • E. Ishikuro

DOI:

https://doi.org/10.33584/rps.13.2006.3113

Abstract

Experimental feeds containing 0, 500, 1000, 1500 or 2000 ppb of lolitrem B derived from perennial ryegrass straw were fed to 9 month-old Japanese Black steers (average liveweight 180 kg) to determine their threshold level of lolitrem B. Steers received feeds containing 1000, 1500 and 2000 ppb of lolitrem B showed signs of ryegrass staggers after 2 to 7 weeks of feeding. The lowest observed adverse effect level (LOAEL) of lolitrem B was approximately 24 μg/kg body weight per day. Only small amounts of lolitrem B residue were detected in muscle, liver, kidney and cerebrum. In contrast, approximately 100 ng/g of lolitrem B was detected in perirenal fat of steers with ryegrass staggers. Keywords: Lolitrem B, Japanese Black cattle, ryegrass staggers, muscle, fat

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Published

2007-01-01

How to Cite

Miyazaki, S., Ikeda, T., Hanazumi, M., Fukumoto, Y., Yamata, T., Mikami, O., Yamanaka, N., Murata, H., Shimada, N., & Ishikuro, E. (2007). Toxicological evaluation of endophyte-infected perennial ryegrass straw to Japanese Black steers. NZGA: Research and Practice Series, 13, 415–418. https://doi.org/10.33584/rps.13.2006.3113

Issue

Vol. 13 (2007): 6th International Symposium on Fungal Endophytes of Grasses

Section

Past volumes

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